CPT procedure code
CPT 45381: Colonoscopy with submucosal injection
Procedure code with common scenarios, denial patterns, and appeal guidance.
Code
45381
Category
surgery
Common scenarios
- Colonoscopy injection
- Colonoscopy with injection
Common denial patterns
- Missing PA where required
- Wrong POS or modifier
Frequently asked questions
What is CPT 45381?
Colonoscopy with submucosal injection
When is it typically billed?
Colonoscopy injection; Colonoscopy with injection.
What are common denial reasons?
Missing PA where required; Wrong POS or modifier.
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